Status:

COMPLETED

Skin Safety Profile of Different Exposure to the Light Emitting Diode (LED) in Healthy Subjects

Lead Sponsor:

L'Oreal

Conditions:

Radiation Tolerance

Skin Aging

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Photomodulation is a process which manipulates or regulates cell activity using light sources without thermal effect. Different studies have investigated the use of non-thermal low dose light emitting...

Detailed Description

The purpose of this study is to evaluate different treatment regimens in order to be able to develop new indications or to optimize the result already obtained in the treatment of wrinkles around the ...

Eligibility Criteria

Inclusion

  • Healthy subjects (male and female) at least 18 years old with skin types range from Fitzpatrick type I-VI (Appendix 1),
  • Subjects must read, understand and sign the informed consent,
  • Subjects must be willing and able to comply with follow up requirements,
  • To be willing to report any medications taken during the study and refrain from taking any medication during the study that might produce photoreactions.

Exclusion

  • Subjects must not have active or localized or systemic infection,
  • Subjects must not be immunocompromised,
  • Subjects must be negative for HIV and hepatitis B and C serology,
  • Subjects must not have history of light activated seizure or migraine headache disorder,
  • Individuals taking medication who have been advised by a physician or pharmacist to avoid sunlight and subjects having vitiligo
  • Subjects must not have mental illness such as schizophrenia or severe depression,
  • Subjects must not have photosensitivity, photoallergy or photodermatitis,
  • Subjects must not be pregnant or breast feeding. Subjects must discuss concerns about birth control with the study physician. Subjects who become pregnant during the study must inform the investigator immediately,
  • Subject must not have a skin condition that the examining Investigator deems inappropriate for participation,
  • Subject must not take part or intend to take part in another study liable to interfere with this study whatever the region of the body considered for 30 days prior to the study start and 30 days following completion of the study,
  • Subjects must not have had GentleWaves treatment, other light treatments (including tanning beds), collagen or other facial tissue augmentation, Botox®, chemical peels, non-ablative (non invasive laser) therapies, dermabrasion, topical antioxidant or other resurfacing procedures at any time during the study,
  • Subject must not refuse to sign the informed consent document and/or refuse to comply with all study requirements,
  • Subjects must not have any previous history of keloïd scarring.

Key Trial Info

Start Date :

June 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00818311

Start Date

June 1 2008

End Date

December 1 2008

Last Update

January 7 2009

Active Locations (1)

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1

Thomas Stephens and Associates, Inc

Carrollton, Texas, United States, 75006