Status:
TERMINATED
Longitudinal Study in Clinically Isolated Syndrome (CIS) Patients Treated With Interferon Beta
Lead Sponsor:
Centre Hospitalier Universitaire de Nice
Conditions:
Clinically Isolated Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study is to evaluate the role of cognitive disorders and quality of life in patients with CIS, considered as high risk to develop an MS, treated with interferon Beta. This prospective ...
Eligibility Criteria
Inclusion
- Patients older than 18 years,
- Patients with CIS and temporo spatial dissemination for less than one year
- Patient without prior immunomodulatory treatment
- Patient informed of CIS diagnosis and MS according to McDonald criteria,
- Patients with EDSS inferior or egal to 5,5
- Patients usually french-reader and with MMS \>24
- Patients informed of study protocol
- Patients agree to sign informed consent
- Patients with affiliation number from social French département.
Exclusion
- Secondary progressive MS
- Patient with acute relapse
- Patient already treated with IFN
- corticosteroids less than 15 days
- Patient with severe dépressive disorders
- Patient already included in clinical study
- Patient \< 18 years
- Patient with known contra indications for beta interféron
- Every reason with can provoke an interruption of the study, regarding a patient empechment
- Contre indications for MRI or other tests required in the study
- pregnancy or lactation
- patient Under juridic protection
Key Trial Info
Start Date :
June 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT00819897
Start Date
June 1 2008
End Date
June 1 2014
Last Update
May 12 2016
Active Locations (17)
Enter a location and click search to find clinical trials sorted by distance.
1
CHU de Bordeaux - Hôpital Pellegrin
Bordeaux, France
2
University hospital of Côte de Nacre
Caen, France
3
Hôpital Gabriel Montpied
Clermont-Ferrand, France
4
Hôpital Général de DIJON
Dijon, France