Status:

COMPLETED

ADX10059 as a Monotherapy in Patients With Gastroesophageal Reflux (GERD)

Lead Sponsor:

Addex Pharma S.A.

Conditions:

Gastroesophageal Reflux

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

Evaluation of the effect of ADX10059 on symptom control in patients with gastroesophageal reflux.

Eligibility Criteria

Inclusion

  • diagnosis of typical GERD
  • well controlled on a standard clinical symptoms controlled dose of PPI treatment
  • body mass index ≤32 kg/m2

Exclusion

  • exclusively atypical symptoms of GERD
  • symptoms that have been shown not to be associated with GERD
  • erosive oesophagitis
  • hiatus hernia \> 3 cm
  • current diagnosis of co-existing psychiatric disease
  • known clinically significant allergy or known hypersensitivity to drugs
  • pregnant or breast-feeding
  • has received sodium valproate or topiramate within 30 days of Screening
  • has a history of a significant medical condition that may affect the safety of the patient or preclude adequate participation in the study

Key Trial Info

Start Date :

December 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT00820079

Start Date

December 1 2008

Last Update

December 24 2009

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Wien

Vienna, Austria

2

Leuven

Leuven, Belgium

3

Bordeaux

Bordeaux, France

4

Lyon

Lyon, France