Status:
COMPLETED
Vancomycin Associated Red Man Syndrome (RMS)
Lead Sponsor:
Children's Mercy Hospital Kansas City
Collaborating Sponsors:
Katherine Berry Richardson Foundation
Conditions:
Red Man Syndrome
Eligibility:
All Genders
6-21 years
Brief Summary
This study proposes to identify patients who developed RMS with vancomycin infusion, and determine presence or absence of variant alleles involved in histamine biotransformation. The implications of t...
Detailed Description
Vancomycin has been utilized as an antimicrobial therapeutic agent for serious gram positive infections for more than half a century.The pharmacokinetics of vancomycin has been well studied, and in ge...
Eligibility Criteria
Inclusion
- Patients must have received vancomycin
Exclusion
- Patients who have received antihistamines at the time of vancomycin administration or
- Patients who have been on steroids or tricyclic antidepressants within 30 days prior to the vancomycin administration
- People receiving ECMO or have multiorgan failure
- Currently receiving dialysis
Key Trial Info
Start Date :
January 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
544 Patients enrolled
Trial Details
Trial ID
NCT00824122
Start Date
January 1 2008
End Date
October 1 2011
Last Update
October 12 2011
Active Locations (1)
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1
Children's Mercy Hospital & Clinics
Kansas City, Missouri, United States, 64108