Status:

COMPLETED

Long-term Efficacy and Safety Study With Oralgen Grass Pollen

Lead Sponsor:

Artu Biologicals

Conditions:

Allergic Rhinoconjunctivitis

Eligibility:

All Genders

18-51 years

Phase:

PHASE2

PHASE3

Brief Summary

This study is designed to give additional information on the efficacy, safety and local effects (tolerability) of a dose of sublingual immunotherapy administered once a day, during a second grass poll...

Detailed Description

Allergy is one of the most common chronic diseases. Allergies to grass, weed, and tree pollens characteristically result in seasonal rhinitis symptoms commonly termed hay fever. The risk of developing...

Eligibility Criteria

Inclusion

  • Patients who meet the in and exclusion criteria for study AB0602 and successfully finished this study.
  • Patients who have given their written consent to participate in this study.
  • Patients who are willing to comply with the protocol and understand the information given.
  • Female patients of childbearing potential are eligible if they are not sexually active or if they use a medically accepted contraceptive method.
  • Negative urine pregnancy test if female at the end of the previous study.

Exclusion

  • Pregnancy, breast-feeding / lactation or sexually active women of childbearing potential who are not using a medically accepted contraceptive method.
  • Patients who were non-compliant during study AB0602.
  • Patients with a past or current disease, which as judged by the investigator, may affect the patient's participation in or the outcome of this study.

Key Trial Info

Start Date :

August 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2009

Estimated Enrollment :

356 Patients enrolled

Trial Details

Trial ID

NCT00824447

Start Date

August 1 2007

End Date

January 1 2009

Last Update

May 5 2010

Active Locations (39)

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Page 1 of 10 (39 locations)

1

MHAT PLovdiv, ENT Clinic

Plovdiv, Bulgaria

2

Military Medical Academy, Clinic of ENT

Sofia, Bulgaria, 1606

3

Military Medical Academy

Sofia, Bulgaria, 1606

4

5th MHAT, ENT Clinic

Sofia, Bulgaria