Status:

COMPLETED

Exploratory Study of Natural Killer Cells in Human Skin

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Atopic Dermatitis

Contact Dermatitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Natural Killer (NK) cells play a unique role during innate immune responses as they are able to recognize and eliminate, without specific sensitization, tumors, microbe-infected cells as well as allog...

Detailed Description

Then, we will define whether these parameters are qualitatively/ quantitatively modified in the following skin pathologies: a) atopic dermatitis; b) contact dermatitis; c) psoriasis ; d) lichen planus...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years.
  • Consent obtained after healthy donor or patient information.
  • Patients suffering from one of the following diseases: a) atopic dermatitis ; b) contact dermatitis; c) psoriasis ; d) lichen planus ; e) GVH ; f) melanoma.

Exclusion

  • Age below 18,
  • pregnant or breastfeeding women,
  • persons under guardianship, persons without social security, prisoners, persons hospitalized without consent on the basis of French laws L. 3212-1 et L. 3213-1. Patients affected by HIV infection, AIDS, Hepatitis A, B or C infection.
  • Neutropenia \<1000/mm3.
  • Thrombopenia \<50 000/mm3.

Key Trial Info

Start Date :

February 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2011

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT00824889

Start Date

February 1 2009

End Date

November 1 2011

Last Update

August 29 2014

Active Locations (1)

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1

Service de Dermatologie- Hopital Sainte Marguerite

Marseille, France, 13385