Status:

COMPLETED

Does Magnetic Resonance Imaging (MRI) Improve Interventional Outcomes for Lumbosacral Radiculopathy?

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

Walter Reed Army Medical Center

Conditions:

Lumbosacral Radiculopathy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Epidural steroid injections (ESI) are the most frequently performed procedures in pain clinics. When performing ESI, there is no consensus about how to best select candidates for this intervention, an...

Detailed Description

One hundred and thirty-one patients referred to the Blaustein Pain Treatment Center with back and leg pain will be randomized to receive one of two treatments. Sixty-three patients will be allocated t...

Eligibility Criteria

Inclusion

  • Age \> 18
  • Candidates for ESI based on history and physical exam
  • NRS pain score \> 4
  • Leg pain \> back pain
  • Patients already have an MRI

Exclusion

  • Untreated coagulopathy
  • Previous spine surgery
  • Leg pain \> 4 years duration
  • Epidural steroid injection within past 2 years
  • Serious (e.g., bowel or bladder incontinence, loss of reflexes) or progressive neurological deficit
  • Referrals from surgery diagnostic injections for surgical evaluation
  • Serious medical (e.g. congestive heart failure) or psychiatric (untreated depression) condition that might preclude optimal outcome
  • Pregnancy
  • Serious underlying pathology (e.g., vertebral fracture, spinal infection or metastases), as determined by an independent reviewer (group I) or the treating physician (group II) on MRI. The investigator and injector for group I patients will remain blinded to this review except to know that serious pathology was ruled out.

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2011

Estimated Enrollment :

131 Patients enrolled

Trial Details

Trial ID

NCT00826124

Start Date

January 1 2009

End Date

February 1 2011

Last Update

June 23 2011

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Walter Reed Army Medical Center

Washington D.C., District of Columbia, United States, 20307

2

Johns Hopkins School of Medicine

Baltimore, Maryland, United States, 21205