Status:
COMPLETED
The Effect of Short Term Amiodarone Treatment After Catheter Ablation for Atrial Fibrillation
Lead Sponsor:
Rigshospitalet, Denmark
Conditions:
Atrial Fibrillation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to examine the overall effectiveness of short-time anti-arrhythmic drug treatment with amiodarone (to control heart rhythm) to prevent short-and long-term atrial fibrillat...
Detailed Description
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with increased mortality and morbidity due to increased risk of stroke, poor quality of life and risk of developing...
Eligibility Criteria
Inclusion
- Patients with symptomatic paroxysmal or persistent atrial fibrillation undergoing catheter ablation for atrial fibrillation. (persistent episodes may last no more than 12 months)
Exclusion
- Contraindication or intolerance to amiodarone.
- Prolonged amiodarone treatment within 3 months before the planned ablation procedure.
- Previous participation in this study.
- Other cardiac arrythmias (patients with co-existing atrial flutter can be included).
- Antiarrhythmic treatment for indication other than atrial fibrillation (or atrial flutter).
- Heart failure (NYHA class III or IV or left ventricular ejection fraction \< 35%).
- Significant heart valve disease.
- Significant lung disease, thyroid dysfunction or liver disease.
- Inability or unwillingness to be treated with anticoagulation before and during the study.
- Females with birth giving potential
- Failure to give informed concent.
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
212 Patients enrolled
Trial Details
Trial ID
NCT00826826
Start Date
January 1 2009
End Date
January 1 2014
Last Update
March 5 2014
Active Locations (2)
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1
Rigshospitalet
Copenhagen, Denmark, 2100
2
Gentofte University Hospital
Hellerup, Denmark, 2900