Status:
COMPLETED
Use of 3D/4D Ultrasound in the Evaluation of Fetal Anomalies
Lead Sponsor:
The University of Hong Kong
Conditions:
Homozygous αº-thalassemia
Hb Bart's Disease
Eligibility:
FEMALE
18-45 years
Brief Summary
Volumetry measurements can be a potential clinical use as non-invasive tools in prenatal diagnosis and screening and helps to reduce the risk and complications of invasive procedures. 3DUS volumetry g...
Detailed Description
Conventionally volume measurements can be made by using multiplanar or VOCALTM (Virtual Organ Computer-aided AnaLysis). Recently, a new technique, XI VOCALTM (eXtended Imaging VOCAL) has been describe...
Eligibility Criteria
Inclusion
- For objective 1 and 2 - Samples are recruited from our prenatal diagnostic clinic at Ysan Yuk Hospital between 11-14 weeks' gestation. They are those who come for routine scan and those who are referred from the general antenatal clinics of the same hospital which pregnancies are at risk of homologous alphaº thalassaemia.
- For objective 3 - Recruitment are the same as above except samples are obtained from normal pregnancy.
- For objective 4 - Recruitment are the same as above. However, study is divided into intervention group and control group. For the intervention group, data is collected from pregnancies at risk of of homozygous αº-thalassemia while for the control group, data is collected from normal pregnancies.
Exclusion
- If women refuse to participate in the study
- Patients with other co-existing illnesses
Key Trial Info
Start Date :
March 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2009
Estimated Enrollment :
195 Patients enrolled
Trial Details
Trial ID
NCT00826917
Start Date
March 1 2008
End Date
August 1 2009
Last Update
June 2 2015
Active Locations (1)
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1
Tsan Yuk Hospital
Hong Kong, Hong Kong, China