Status:

COMPLETED

Obesity, Oral Contraception, and Ovarian Suppression

Lead Sponsor:

Columbia University

Collaborating Sponsors:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Ovarian Suppression

Eligibility:

FEMALE

18-35 years

Phase:

PHASE4

Brief Summary

This study proposes a double blind randomized clinical trial to include normal weight and obese women who have normal ovulatory function at baseline; the investigators will randomize women to 2 widely...

Detailed Description

There is a large gap between lowest expected failure rates of about 1.5% and typical use failure rates of about 7% per year. This gap may be due to incorrect use or to decreased oral contraceptive (OC...

Eligibility Criteria

Inclusion

  • Aged 18-35
  • Body Mass Index (BMI) 19-24.9 or 30-39.9 kg/m\^2
  • Willing to take birth control pills for 3-4 months
  • Recent spontaneous pregnancy or cyclic menses

Exclusion

  • Contraindications to hormonal contraceptives
  • Oophorectomy/Polycystic ovary syndrome (PCOS)
  • Taken oral contraceptives to regulate menses recently
  • Weight reduction surgery
  • Used Depo-Provera within the last 12 months
  • Pregnant or currently breastfeeding
  • Desiring pregnancy within the next 4 months
  • Unable to make study visit commitment
  • Previous participation in this study

Key Trial Info

Start Date :

July 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

226 Patients enrolled

Trial Details

Trial ID

NCT00827632

Start Date

July 1 2006

End Date

December 1 2008

Last Update

April 30 2019

Active Locations (1)

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1

Columbia University Medical Center

New York, New York, United States, 10032