Status:
COMPLETED
Echocardiographic Evaluation of Hypertensive Acute Pulmonary Edema
Lead Sponsor:
Carol Davila University of Medicine and Pharmacy
Collaborating Sponsors:
Ministry of Education, Research, Youth and Sport, Romania
Conditions:
Pulmonary Edema
Hypertension
Eligibility:
All Genders
18+ years
Brief Summary
Acute cardiogenic pulmonary edema (ACPE), one of the most severe forms of acute heart failure, represents 5% of hospital admissions. One of the most frequent phenomena encountered during ACPE is hyper...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- acute onset of dyspnea within the preceding 8 hours
- respiratory distress and pulmonary rales at any level
- pulmonary congestion confirmed by chest radiography
- systolic blood pressure \> 160 mmHg before treatment
- sinus rhythm
- signed informed consent
- Exclusion criteria:
- acute myocardial infarction confirmed by myocardial necrosis markers (either CKMB or troponin I). Angina pectoris alone will not be excluded
- significant left sided valvular disease (more than moderate). Mitral regurgitation of any severity will not be excluded, due to the hypothesis of the role of dynamic mitral regurgitation in the pathogenesis of acute hypertensive pulmonary edema
- congenital heart disease
- cardiac tamponade
- rhythm and conduction disturbances that may have precipitated pulmonary edema, like sustained ventricular tachycardia and complete heart block
Exclusion
Key Trial Info
Start Date :
May 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT00829855
Start Date
May 1 2008
End Date
May 1 2009
Last Update
March 5 2013
Active Locations (1)
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1
Department of Cardiology, University and Emergency Hospital of Bucharest
Bucharest, Romania, 050098