Status:

WITHDRAWN

A Study To Examine The Safety And Efficacy Of PF-00610355 In Moderately Asthmatic Subjects

Lead Sponsor:

Pfizer

Conditions:

Asthma, Bronchial

Lung Diseases, Obstructive

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

This study (A7881006) is the first multiple dose study in moderate asthmatic subjects and aims to determine the safety and efficacy of PF-00610355 when subjects take PF-00610355 on a daily basis for 4...

Eligibility Criteria

Inclusion

  • Subjects with a physician documented history or diagnosis of persistent asthma for at least 6 months prior to Screening Visit 1.
  • Trough FEV1 must be 50-100% of predicted at Screening Visit 1.
  • Subjects who have been maintained on a stable dose of ICS over the previous month prior to screening.

Exclusion

  • Subjects who have had a severe asthma exacerbation in the 2 months prior to screening.
  • Subjects meeting any of the criteria of 'very poorly controlled' according to the NIH EPR 3 guidelines.
  • Subjects with evidence or history of cardiovascular disease including angina, myocardial, infarction, clinically significant cardiac arrhythmia (eg, atrial fibrillation, atrial flutter,supraventricular tachycardia, ventricular tachycardia), systemic hypertension (SBP \> 160 mmHg or DBP \>100mmHg), pulmonary hypertension or cerebrovascular disease (including transient ischaemic attacks).

Key Trial Info

Start Date :

April 15 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2009

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00830427

Start Date

April 15 2009

End Date

December 31 2009

Last Update

January 31 2019

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