Status:

UNKNOWN

Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung Disease

Lead Sponsor:

Kolding Sygehus

Collaborating Sponsors:

Regionshospitalet Holstebro, Holstebro, Denmark

Odense University Hospital

Conditions:

Healthy Volunteers

Heart Failure

Eligibility:

All Genders

30-80 years

Brief Summary

The purpose of the study is to determine whether the excretion of renal water- and salt-channels in the urine reflects the handling of water and salt in the kidneys, and whether the excretion can be u...

Detailed Description

The purpose of the study is to determine whether the excretion of renal water- and salt-channels (Aquaporin-2 and Epithelial Sodium Channels) in the urine accurately reflects the handling of water and...

Eligibility Criteria

Inclusion

  • Symptomatic heart failure
  • Severe valvular aortic stenosis
  • Acute Coronary Syndrome
  • Medically refractory chronic angina pectoris or pulmonary hypertension with preserved left ventricular function

Exclusion

  • Pregnancy
  • Drug abuse
  • Malignant disease
  • Significant disease of other organs including endocrine diseases

Key Trial Info

Start Date :

February 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2012

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT00830726

Start Date

February 1 2009

End Date

February 1 2012

Last Update

June 23 2011

Active Locations (1)

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1

Kolding Hospital

Kolding, Denmark, DK-6000