Status:

COMPLETED

Double-Blind Study of Topical WBI-1001 Cream on Patients With Psoriasis

Lead Sponsor:

Welichem Biotech Inc.

Conditions:

Psoriasis

Eligibility:

All Genders

18-65 years

Brief Summary

The purpose of this study is to evaluate primarily the safety and tolerability and secondarily the efficacy of topically applied WBI-1001 cream in patients with mild to moderate psoriasis. Double-blin...

Detailed Description

Patients initiated screening within 4 weeks of commencing study treatment. Based on progression of the study, at day 0 patients were assigned to one of six treatment Cohorts. Patients were randomized ...

Eligibility Criteria

Inclusion

  • PGA score at day 0 must be 2,3 or 4.
  • In good overall health.
  • Women of child bearing potential to have negative serum beta-human chorionic gonadotropin pregnancy test before randomization
  • Must be prepared to use adequate means of contraception
  • Must not be lactating.
  • Male partners of females in the study must be prepared to use adequate means of contraception.
  • Must comply with study protocol and attend all visits.
  • Provide written consent prior to participating in the study.

Exclusion

  • Spontaneously improving or rapidly deteriorating psoriasis.
  • Patients with other diseases (especially dermatological, immunodeficiency or neurological/psychiatric) that might interfere with assessment of plaque psoriasis.
  • Systemic immunomodulatory therapy in past 36 weeks, phototherapy in past 4 weeks, various psoriatic chemotherapies and beta blockers in the past 2 weeks

Key Trial Info

Start Date :

July 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT00830817

Start Date

July 1 2007

End Date

June 1 2008

Last Update

January 28 2009

Active Locations (1)

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1

Innovaderm Research inc.

Montreal, Quebec, Canada, H2K 4L5