Status:

COMPLETED

Beta-2 Microglobulin and Serum Cytokines x HAART

Lead Sponsor:

UPECLIN HC FM Botucatu Unesp

Collaborating Sponsors:

Faculdade de Medicina de Botucatu, UNESP, Botucatu, Brasil

Conditions:

HIV Patients

Eligibility:

All Genders

18-80 years

Brief Summary

Cross-sectional study to assess the behavior of Beta-2 microglobulin and serum cytokines TNF-α, IFN-γ, IL-2, IL-4 and IL-10 as indicators of highly active antiretroviral therapy (HAART) failure.

Detailed Description

Objective: To assess the behavior of Beta-2 microglobulin and serum cytokines TNF-α, IFN-γ, IL-2, IL-4 and IL-10 as indicators of highly active antiretroviral therapy (HAART) failure Design: Cross-sec...

Eligibility Criteria

Inclusion

  • HIV-1-infected individuals
  • Over 18 years old
  • Sign the "written consent form" (WCF)

Exclusion

  • Do not presenting other immunosuppression causes, such as neoplasias, transplantations
  • Do not presenting treatment by immunosuppressive substances
  • Do not presenting auto-immune diseases
  • Not be using any type of immunostimulating substances
  • Not at any time of gestation

Key Trial Info

Start Date :

August 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

109 Patients enrolled

Trial Details

Trial ID

NCT00831207

Start Date

August 1 2004

End Date

December 1 2008

Last Update

January 28 2009

Active Locations (1)

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Faculdade de Medicina de Botucatu - UNESP

Botucatu, São Paulo, Brazil, 18618-970