Status:

COMPLETED

Phase I Combination Ixabepilone + Cisplatin

Lead Sponsor:

R-Pharm

Conditions:

Non Small Cell Lung Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

The purpose of this study is to determine the highest dose of ixabepilone that can be given safely with cisplatin without causing severe or life-threatening side effects and for some patients with non...

Eligibility Criteria

Inclusion

  • Escalation Phase Subjects: Primary solid tumor not curable by local measures such as surgery, radiation
  • Inclusion Criteria:
  • Men and women age ≥ 18
  • Exclusion:
  • More than 2 prior chemotherapy containing regimens for metastatic disease
  • No prior exposure to cisplatin or ixabepilone
  • Expansion Phase Subjects: Advanced Non-small cell lung cancer
  • Inclusion Criteria:
  • Men and women age ≥ 18
  • Exclusion:
  • No prior chemotherapy-containing regimen for metastatic disease
  • No prior exposure to cisplatin or ixabepilone

Exclusion

    Key Trial Info

    Start Date :

    May 1 2009

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2011

    Estimated Enrollment :

    30 Patients enrolled

    Trial Details

    Trial ID

    NCT00832117

    Start Date

    May 1 2009

    End Date

    January 1 2011

    Last Update

    October 28 2020

    Active Locations (7)

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    Page 1 of 2 (7 locations)

    1

    Georgetown University Medical Center

    Washington D.C., District of Columbia, United States, 20007

    2

    The Cancer Institute Of New Jersey

    New Brunswick, New Jersey, United States, 08901

    3

    Penn State Milton S. Hershey Medical Center

    Hershey, Pennsylvania, United States, 17033

    4

    Local Institution

    Lucca, Italy, 55100