Status:
UNKNOWN
Effect of Glucosamine or Ibuprofen Combined With Physical Training in Patients With Knee-Osteoarthritis
Lead Sponsor:
Bispebjerg Hospital
Collaborating Sponsors:
Lund University
The Danish Rheumatism Association
Conditions:
Osteoarthritis of the Knee
Eligibility:
All Genders
50-70 years
Phase:
PHASE1
Brief Summary
The investigators will investigate the effect of glucosamine or ibuprofen combined with 12 weeks of muscle strength-training in patients with knee-osteoarthritis. The investigators would like to eluc...
Eligibility Criteria
Inclusion
- Age 50 to 70 years
- Bilateral tibiofemoral osteoarthritis of the knee on x-ray
- American College of Rheumatology (ACR) clinical classification criteria
Exclusion
- Severe health problems such as cardiovascular disease, active cancer, diabetes, kidney or liver diseases
- Excess alcohol use (\> 21 alcoholic drinks per week)
- Severe overweight (BMI \> 35)
- History of injury or operation in the knee, planned knee-joint replacement, other rheumatologic diseases, previous gastric ulcer, allergy to the contents of ibuprofen or glucosamine, regular strength training prior to the inclusion
Key Trial Info
Start Date :
February 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00833157
Start Date
February 1 2005
End Date
March 1 2009
Last Update
January 30 2009
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