Status:
COMPLETED
Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Septic Shock
Severe Sepsis
Eligibility:
All Genders
18+ years
Brief Summary
Severe sepsis and septic shock are causes of admission in intensive care units.Modification of natriuretic peptid including NT-proBNP and cardiac autonomic nervous system alteration are reported in se...
Detailed Description
Our principal aim is to characterize modulation of cardiac sympathic nervous system in sepsis through the study of sinusal change and myocardiac fixing of MIBG. The second aim is 1)to assess links be...
Eligibility Criteria
Inclusion
- Patient over 18 years admitted in intensive care unit and having severe sepsis criteria or septic shock documented or suspected define as Bone Criteria
- hemodynamically stable situation
- sinusal rhythm
- Patient for social security
Exclusion
- Minors
- Patient under guardianship or trusteeship
- pregnant or lactating women
- diabetic
- cardiomyopathy known and/or treated or detect in admission
- electro-systolic process permanent or transitory
- neurological history or degenerative pathology
- chronic respiratory insufficiency
- Chronic renal insufficiency
Key Trial Info
Start Date :
October 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT00835913
Start Date
October 1 2008
End Date
September 1 2011
Last Update
January 19 2015
Active Locations (1)
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1
University Hospital Grenoble
Grenoble, France, 38000