Status:
COMPLETED
Sampling Biomarkers in Meniscus Injury to the Knee
Lead Sponsor:
Scuderi, Gaetano J., M.D.
Collaborating Sponsors:
Stanford University
Conditions:
Cartilage Diseases
Eligibility:
All Genders
18-90 years
Brief Summary
The diagnosis of clinically-significant meniscal tears of the knee remains challenging, and it is unknown why only some injuries become painful. The limitations of diagnostic magnetic resonance imagin...
Detailed Description
Lavage of the operative and contralateral knee for comparison was performed under anesthesia prior to arthroscopy by the infusion of sterile saline into the knee joint followed by the immediate withdr...
Eligibility Criteria
Inclusion
- Adult patients with knee pain \< 6 months with acute onset who had failed conservative treatment and elected for arthroscopic management. Indications for surgery included the presence of mechanical symptoms on history, a physical examination positive for McMurray's maneuver or joint line tenderness or both32, absence of severe joint space narrowing on plain radiography1 33, and the presence of grade III signal changes on MRI35 in an anatomic location consistent with the history and physical examination.
Exclusion
- Less than 18 years old.
- Recent (within three months) intra-articular corticosteroid injection and past or current medical history of autoimmune disease (i.e. rheumatoid arthritis).
- In addition, no patients involved in a worker's compensation claim or personal injury litigation were enrolled in the study.
Key Trial Info
Start Date :
June 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2007
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT00836966
Start Date
June 1 2006
End Date
June 1 2007
Last Update
February 4 2009
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