Status:

COMPLETED

Exercise Intolerance in Obstructive Sleep Apnea Syndrome Patients

Lead Sponsor:

University Hospital, Grenoble

Collaborating Sponsors:

AGIR à Dom

Conditions:

Obstructive Sleep Apnea

Eligibility:

All Genders

40-65 years

Phase:

NA

Brief Summary

The syndrome of obstructive sleep apnea (OSAS) is a public health problem that affects 2 to 4% of the general population. The patients with OSAS frequently complain of intolerance to exercise muscle f...

Detailed Description

Study type : Physiopathology trial Study design : Prospective randomized controled trial Expected Total Enrollment : 45 patients + 15 control subjects Tested treatment : Physical exercise program (4...

Eligibility Criteria

Inclusion

  • Ages Eligible for Study : 18 Years and above
  • Genders Eligible for Study: Both
  • Non obese : body mass index (BMI \< 30 kg/m2)
  • Sedentary subjects : less physical activity than 30 minutes 3 time a week
  • and VOORIPS physical activity level questionnaire score \< 9.
  • Obstructive sleep apnea syndrome (OSAS) patients :
  • Recently diagnosed (\< 3 months)
  • AHI \> 30 / hour (polysomnographic monitoring measurement)

Exclusion

  • Excessive daytime sleepiness (Epworth score \> 12)
  • Cardiovascular pathology (except controlled hypertension)
  • Pathology interacting with physical activity
  • Diabetes (known or treated)
  • Other participation to a clinical trial at the same

Key Trial Info

Start Date :

June 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2012

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00837018

Start Date

June 1 2005

End Date

May 1 2012

Last Update

March 5 2013

Active Locations (1)

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CHU, medecine du sport

Grenoble, France, 38000