Status:
COMPLETED
Muscle Ultrasound: A New Tool for Measuring Progression in Amyotrophic Lateral Sclerosis (ALS)
Lead Sponsor:
Vanderbilt University
Conditions:
Amyotrophic Lateral Sclerosis
Eligibility:
All Genders
18+ years
Brief Summary
This is a study in patients with Amyotrophic Lateral Sclerosis (ALS). We will use muscle ultrasound as a tool to try and see if there are changes in muscle size that can find out how fast ALS is progr...
Detailed Description
Protocol for the Study - Muscle Ultrasound: A New Tool for Measuring Progression in ALS A. Specific Aims The authors propose to study the change in muscle mass over time in patients with ALS. Muscle ...
Eligibility Criteria
Inclusion
- must meet the El Escorial criterion for definite or probable ALS.
- forced vital capacity (FVC) must exceed 50%.
Exclusion
- Patients with primary lateral sclerosis (PLS) and other forms of motor neuron disorders
- severe weakness from ALS who require continuous mechanical ventilation, who have a forced vital capacity less than 50%, or who have no clinically measurable strength in the arms and legs.
- Patients without cognitive capacity to give informed consent. (This is not a clinical feature of ALS, and therefore such patients would have an alternate diagnosis that would prevent such capacity.)
Key Trial Info
Start Date :
February 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2009
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00838617
Start Date
February 1 2009
End Date
August 1 2009
Last Update
December 11 2009
Active Locations (1)
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1
ALS Clinic, Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232