Status:
COMPLETED
Activity and Content of Factor VIII (FVIII) in Human Plasma: The Assessment of a Novel Immunoassay
Lead Sponsor:
Children's Hospital Los Angeles
Collaborating Sponsors:
University of Vermont
Conditions:
Hemophilia A
Eligibility:
MALE
18+ years
Phase:
NA
Brief Summary
A novel immuno-assay is being evaluated for the measurement of Factor VIII. Current procedure measures a rate assay which is subject to much artefact. The hypothesis is that the new assay will give a ...
Detailed Description
Remnant samples collected in a clinical laboratory are assayed with the new procedure and compared with the standard functional activated partial thromboplastin time (APTT) assay. A PK study in seven ...
Eligibility Criteria
Inclusion
- adults with hemophilia A
- factor VIII less that 2%
- informed consent signed
- absence of an inhibitor
Exclusion
- history of a high responding inhibitor anemia
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2009
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT00839202
Start Date
September 1 2006
End Date
February 1 2009
Last Update
February 1 2017
Active Locations (1)
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1
Department of Biochemistry University of Vermont
Burlington, Vermont, United States, 05446