Clopidogrel Resistance and the Possibility of Its Affection

Status:

TEMPORARILY_NOT_AVAILABLE

Clopidogrel Resistance and the Possibility of Its Affection

Lead Sponsor:

Charles University, Czech Republic

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18-90 years

Brief Summary

The purpose of the study is to determine, whether the resistance to clopidogrel could be affected by higher doses of this drug, or by replacement of clopidogrel with another ADP-antagonist ticlopidine...

Detailed Description

Patients after percutaneous coronary intervention (PCI) with stent implantation have to be treated by dual antiplatelet therapy, which standard part represents clopidogrel. The response to clopidogrel...

Eligibility Criteria

Inclusion

written informed consent
coronary artery disease verified by coronary angiography
percutaneous coronary intervention with stent implantation
standard indication for dual antiplatelet therapy

Exclusion

scheduled surgical revascularization by aortocoronary bypass
insufficient cooperation of the patient
coagulopathy in history with a higher risk of bleeding
life expectancy shorter than 1 year
severe anemia with hemoglobin level\< 10,0 g/dl
platelet count \< 100,000)

Key Trial Info

Start Date :

Trial Type :

EXPANDED_ACCESS

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00839345

Last Update

February 1 2019

Active Locations (1)

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