Status:

COMPLETED

Study to Investigate the Efficacy of Symbicort® SMART.

Lead Sponsor:

AstraZeneca

Conditions:

Asthma

Eligibility:

All Genders

16+ years

Phase:

PHASE3

Brief Summary

The primary objective of this study is to compare the efficacy of Symbicort SMART (Symbicort Turbuhaler 160/4.5μg, one inhalation twice daily plus as needed) with Symbicort Turbuhaler 160/4.5μg, one i...

Eligibility Criteria

Inclusion

  • Diagnosis of asthma according to the Global Initiative for Asthma guidelines (GINA) 2007 with a documented history of at least 6 months duration.
  • Reversible airway obstruction, defined as an increase in FEV1 ≥12% relative to baseline for all patients 15-30 minutes after inhalation of in total 2 x 0.4 mg terbutaline Turbuhaler
  • Prescribed use of inhaled glucocorticoid steroid (GCS) (any brand) for at least 12 weeks.

Exclusion

  • Respiratory infection affecting the asthma, as judged by the investigator, within 4 weeks.
  • Intake of oral, rectal or parenteral GCS within 4 weeks and/or depot parenteral GCS within 12 weeks.

Key Trial Info

Start Date :

February 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2011

Estimated Enrollment :

2091 Patients enrolled

Trial Details

Trial ID

NCT00839800

Start Date

February 1 2009

End Date

February 1 2011

Last Update

November 30 2012

Active Locations (109)

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Page 1 of 28 (109 locations)

1

Research Site

Buenos Aires, Argentina, Argentina

2

Research Site

Capital Federal, Buenos Aires, Argentina

3

Research Site

Mar del Plata, Buenos Aires, Argentina

4

Research Site

Monte Grande, Buenos Aires, Argentina