Status:
COMPLETED
Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Lead Sponsor:
The Cleveland Clinic
Conditions:
Spine Surgery
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is determine if epidural anesthesia administered after surgery or lidocaine administered during surgery will decrease inflammation after spinal surgery and decrease the need ...
Detailed Description
According to a survey of 1570 U.S neurosurgeons, in the United States about 527.000 spine surgeries were done in 1999. This represents close to 65% of the procedures performed by neurosurgeons. Furthe...
Eligibility Criteria
Inclusion
- 18 to 75 years old at time of surgery - adult patients differ from pediatric patients in that adult spines are stiffer than pediatric patient.
- Elective spine surgery
- Two levels laminectomies or above with or without fusion or instrumentatioN
- General anesthesia
- Surgery performed at Cleveland Clinic with informed consent signed prior to sedation or anesthesia - consistent surgical team
Exclusion
- contraindication to lidocaine such as substantial hepatic impairment (ALT or AST more than twice normal)
- renal impairment (serum creatinine \>2 mg/dl),
- seizure disorder requiring medication within 2 years
- planned epidural anesthesia or analgesia
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT00840996
Start Date
May 1 2008
End Date
February 1 2012
Last Update
December 23 2016
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195