Status:
COMPLETED
Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute
Lead Sponsor:
Turku University Hospital
Conditions:
Bone Neoplasm
Eligibility:
All Genders
18+ years
Brief Summary
This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone def...
Detailed Description
This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone def...
Eligibility Criteria
Inclusion
- Patients with primary or recurrent benign bone tumor or tumor-like condition that requires operative treatment by means of tumor evacuation and defect filling
- Pathological fractures of patients in Stratum I are treated by means of conservative treatment for three months before tumor surgery
Exclusion
- History of acute or chronic local infection
- History of malignancy (excluding carcinoma basocellular) within past 5 years
- A history of local radiotherapy
- A known metabolic skeletal disease (such as osteoporosis, Paget's disease or osteomalacia)
- Medication affecting bone turnover (oral bisphosphonates, PTH, sodium fluoride, strontium ranelate, calcitonin, testosterone, systemic cortico- or anabolic steroids)
- Any plans to use phenol or other chemical/thermal method of local tumor control
- Pregnancy
- Any other condition that in the judgment of the investigator, would prohibit the subject from participating in the study or may hinder the collection of data and interpretation of the results
Key Trial Info
Start Date :
March 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00841152
Start Date
March 1 2009
End Date
December 1 2018
Last Update
March 16 2021
Active Locations (5)
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1
Helsinki University Hospital
Helsinki, Finland, 00029
2
Kuopio University Hospital
Kuopio, Finland, 70211
3
Oulu University Hospital
Oulu, Finland, 90220
4
Tampere University Hsopital
Tampere, Finland, 33521