Status:
UNKNOWN
Role of Heme Oxygenase in the Pathogenesis of Hepatocellular Injury in Chronic Hepatitis C Virus (HCV) Infection
Lead Sponsor:
Charles University, Czech Republic
Collaborating Sponsors:
IGA MZ, Czech Republic
Conditions:
Chronic HCV Infection
Nonalcoholic Steatohepatitis
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
In the presented project, the role of heme oxygenase 1 and 2 in the procesess associated with fibroproduction in the chronic HCV infection will be studied. Heme oxygenase expression will be evaluated ...
Detailed Description
Hepatitis C virus (HCV) is a single stranded positive RNA virus belonging to the Flaviviridae family. HCV is a major cause of chronic hepatitis and progressive liver fibrosis leading to cirrhosis. Cur...
Eligibility Criteria
Inclusion
- chronic HCV infection
- must undergo liver biopsy
- must undergo antiviral treatment
Exclusion
- liver sample not obtained
- blood samples for HCV testing not obtained in specified time points during antiviral therapy
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00842205
Start Date
January 1 2007
End Date
December 1 2009
Last Update
February 12 2009
Active Locations (1)
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1
Cetral Military Hospital
Prague, Czechia, 16202