Status:

COMPLETED

Fluid Intake in Kidney Failure

Lead Sponsor:

Medical University of Vienna

Conditions:

Chronic Renal Failure

Kidney Transplantation

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Patients with renal impairment are usually advised to increase their fluid intake. There is currently, however, no evidence supporting this recommendation. In contrast,high fluid intake could be dange...

Eligibility Criteria

Inclusion

  • Patients with native kidney disease or chronic kidney transplant failure
  • An effective glomerular filtration rate (eGFR) according the MDRD formula between 20 and 75ml/min/1.73m2
  • Ejection fraction \>20%
  • Absence of liver cirrhosis or ascites
  • No evidence of active glomerulonephritis or immunosuppressive therapy if native kidney disease
  • Acute transplant rejection
  • Urinary protein excretion below 3g/d
  • Age between 18 and 70 years.

Exclusion

  • Therapy resistant edema
  • Severe pulmonary disease
  • Mean arterial pressure (MAP) \> 120 mm Hg
  • Pregnancy
  • Kidney transplantation within three months prior to randomization

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT00842322

Last Update

February 13 2009

Active Locations (1)

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Medical University Vienna

Vienna, Austria, 1090