Status:

COMPLETED

COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest

Lead Sponsor:

University of Leipzig

Conditions:

Cardiac Arrest

Hypothermia

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

Sudden cardiac arrest (SCA) remains one of the major leading causes of death. Cognitive deficits are common in survivors of SCA. Postresuscitative mild induced hypothermia (MIH) lowers mortality and r...

Detailed Description

Consecutive patients with restoration of spontaneous circulation (ROSC) after resuscitation due to out-of-hospital SCA, admitted to our intensive care unit, underwent MIH. Hypothermia was induced by i...

Eligibility Criteria

Inclusion

  • ROSC after SCA due to VF/VT or PEA/Asystolia
  • GCS 3

Exclusion

  • Non-cardiac SCA
  • Pregnancy
  • Unstable Circulation instead of High-dose Inotropics
  • Life-expectancy reducing concomitant illness

Key Trial Info

Start Date :

April 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2010

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT00843297

Start Date

April 1 2008

End Date

January 1 2010

Last Update

February 2 2010

Active Locations (1)

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1

University of Leipzig, Heart Center, Cardiology

Leipzig, Germany, 04289