Status:
COMPLETED
A Cross-sectional Study of the Occurrence and Effect of Obstructive Sleep Apnea in Subjects With Resistant Hypertension
Lead Sponsor:
The University of Hong Kong
Conditions:
Obstructive Sleep Apnea
Resistant Hypertension
Eligibility:
All Genders
18-65 years
Brief Summary
This study aims to investigate the prevalence of obstructive sleep apnea (OSA) in subjects with resistant hypertension and to evaluate the relationship between parameters of OSA severity and blood pre...
Detailed Description
Obstructive sleep apnea (OSA) is characterized by intermittent upper airway collapse during sleep, which results in hypoxia, arousals and surge in sympathetic activity. There is robust evidence to sup...
Eligibility Criteria
Inclusion
- ≧ 3 anti-HT drugs
- age 18-65
- mentally fit for signing an informed written consent
Exclusion
- moderate renal impairment (glomerular filtration rate \<30 mL/min/m2 )
- endocrine/renal/cardiac causes of secondary HT
- congestive heart failure and clinically fluid overloaded
- On drugs that elevate BP e.g. alcohol, NSAID, steroid
Key Trial Info
Start Date :
February 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2012
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT00843583
Start Date
February 1 2009
End Date
December 1 2012
Last Update
May 3 2017
Active Locations (1)
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1
Department of Medicine, The University of Hong Kong, Queen Mary Hospital
Hong Kong, Hong Kong, 852