Status:
UNKNOWN
Molecular Investigation of Non Alcoholic Fatty Liver Diseases in Obese Patients
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
Liver Disease
Eligibility:
All Genders
18-60 years
Brief Summary
Non alcoholic fatty liver diseases (NAFLD) are represented by two main pathological conditions, hepatic steatosis (HS) and non alcoholic steatohepatitis (NASH), which are characterized by the accumula...
Eligibility Criteria
Inclusion
- Group T(n=30): patient without central adiposity, without insulin resistance, operated for cholecystectomy or a benign liver tumor
- Group A (n=30): patient with central adiposity, insulin resistance and hepatic steatosis (histology).
- Group B (n=30): patient with central adiposity, insulin resistance and steatohepatitis ± hepatic fibrosis (histology).
Exclusion
- viral or autoimmune hepatitis
- hematochromatosis
- alcohol consumption (\> 20 g/24h women, \>30 g/24h men)
- type 1 diabetes
- inflammation or infection before procedure
- abnormal hemostasis or coagulation- pregnancy
Key Trial Info
Start Date :
February 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2011
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00844779
Start Date
February 1 2009
End Date
January 1 2011
Last Update
April 27 2009
Active Locations (2)
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1
Service d'Hépato-Gastro-Entérologie - Nouvel Hôpital Civil
Strasbourg, France, 67091
2
Service de Chirurgie Digestive et Endocrinienne - Nouvel Hôpital Civil
Strasbourg, France, 67091