Status:
COMPLETED
A Comparison of Bupivacaine and 2-chloroprocaine for Spinal Anesthesia
Lead Sponsor:
Université de Montréal
Collaborating Sponsors:
Centre hospitalier de l'Université de Montréal (CHUM)
Conditions:
Spinal Anesthesia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to compare the efficacity and the readiness for discharge between two local anesthetics, bupivacaine and 2-chloroprocaine, used for spinal anesthesia.
Detailed Description
Many surgeries are performed under spinal anesthesia, including ambulatory surgeries. The standard agent used for spinal anesthesia is called bupivacaine. It's safe and effective, but has a major disa...
Eligibility Criteria
Inclusion
- patients aged 18 years and older
- urologic elective ambulatory procedure. For example:cystoscopy, circumcision,transurethral bladder tumor resection, varicocele and hydrocele surgery
- gynecologic elective ambulatory procedure. For example: hysteroscopy, vulvar ou vaginal biopsy
- general surgery elective ambulatory procedure. For example:inguinal herniorraphy, short ano-rectal procedure
Exclusion
- INR \> 1,3
- platelet \< 75 000
- concomitant drugs: clopidogrel (last dose \< 7 days), iv heparin, low molecular weight heparin (last dose \< 24 hours)
- neurologic disease: spinal stenosis, symptomatic lumbar herniated disc, multiple sclerosis
- liquid restriction (cardiac or renal insufficiency)
- allergy or intolerance to chloroprocaine, bupivacaine or PABA
- atypical plasma cholinesterase or deficiency
Key Trial Info
Start Date :
February 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT00845962
Start Date
February 1 2009
End Date
July 1 2009
Last Update
January 27 2010
Active Locations (1)
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1
St-Luc Hospital CHUM
Montreal, Quebec, Canada, H2X 3J4