Status:

COMPLETED

Postprandial Endothelial Dysfunction After a High-Fat Meal in HIV-infected Men

Lead Sponsor:

Tufts University

Conditions:

HIV Infection

Cardiovascular Risk

Eligibility:

MALE

18+ years

Brief Summary

The purpose of this study is to examine the postprandial (anytime after a meal) effect of different dietary fats on endothelial function in HIV-infected and HIV-uninfected men.

Detailed Description

This study requires two visits. Once determined eligible by the study criteria, during the first visit the participant will be randomly placed to receive one of two high-fat meals. The participant wil...

Eligibility Criteria

Inclusion

  • HIV-positive white male aged \>18 years
  • Under one of the following treatment categories:
  • Treatment naive or have never taken any HIV medications
  • Taking Kaletra
  • Taking Sustiva
  • Taking Atripla

Exclusion

  • Smoker
  • Pre-existing diagnosis or treatment for the following:
  • Lipid disorder
  • Cardiovascular disease
  • High blood pressure
  • Diabetes
  • Acute opportunistic infection or malignancy within last 3 months or current therapy for either
  • Active IV drug use

Key Trial Info

Start Date :

January 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2010

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00846599

Start Date

January 1 2008

End Date

January 1 2010

Last Update

October 12 2017

Active Locations (1)

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1

Tufts University

Boston, Massachusetts, United States, 02111