Status:
COMPLETED
Comparision of Different Dose of Neostigmine at Advanced Decurarization
Lead Sponsor:
Centre Hospitalier Departemental Vendee
Conditions:
Anesthesia
Eligibility:
All Genders
18-75 years
Phase:
PHASE3
Brief Summary
Neuromuscular blockers (NMB) are currently used in anesthesia. Residual paralysis (RP) due to NMB is responsible for respiratory disorders after extubation. Neuromuscular blockade is monitored by trai...
Eligibility Criteria
Inclusion
- patient \> 18 years
- informed consent signed
- Patient undergoing any type of scheduled surgery under general anesthesia for which curarization with eventually a maintenance is indicated
- ASA score between I to III
Exclusion
- patient \> 75 years and \< 18 years
- body mass index \> 32 mg/m²
- neurology disease, neuromuscular or muscular disease
- peripheral neuropathy
- coronary heart disease
- asthma
- familial history of malign hyperthermia
- difficulty of intubation and ventilation
- full stomach
- known or suspected allergy to one of the study drug
- mecanique obstruction of digestive or urinary tract
- open-angle glaucoma
- patient with risk of urinary retention linked to urethra-prostatic disorder
- concomittant medication with a influence known on neuromuscular (aminosid, anti-convulsif and corticosteroid
- child bearing women or nursing mother
- no affiliation at a social security
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2009
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT00847938
Start Date
March 1 2009
End Date
November 1 2009
Last Update
May 29 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
CHD Vendée
La Roche-sur-Yon, France, 85925