Status:
COMPLETED
A Study to Obtain Normal Values of Inflammatory Variables From Healthy Subjects
Lead Sponsor:
University Medical Center Groningen
Conditions:
Asthma
Copd
Eligibility:
All Genders
18-80 years
Brief Summary
Smoking induces an inflammatory reaction in the airways which can ultimately result in persistent damage and the development of a Chronic Obstructive Pulmonary Disease (COPD). However, not all subject...
Eligibility Criteria
Inclusion
- Have not smoked during the last year.
- Have never smoked for as long as a year.
- Have \< 0.5 packyear.
Exclusion
- Persons who used inhaled or oral corticosteroids during \>5 years, or within the last 5 years.
- FEV1 \<1.2 L
- A subject is not eligible to enter and participate if he does not agree that we inform his general practicioner about participation in the study and also about any unexpected finding during the study.
- Upper respiratory tract infection (e.g. colds), within 2 months.
- Pregnancy, or the possibility of being pregnant (i.e. women who do not use adequate anticonception as judged by the investigator).
- Malignancy within the past 5 years (except for squamous or basal cell carcinoma of the skin that has been treated with no evidence of recurrence).
- Signs or symptoms of any other concomitant disease that, in the eyes of the investigator, can interfere with the study results.
- Known recent substance abuse (drug or alcohol).
- Claustrophobia.
Key Trial Info
Start Date :
April 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2015
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00848406
Start Date
April 1 2009
End Date
January 1 2015
Last Update
January 16 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Medical Centre Groningen
Groningen, Provincie Groningen, Netherlands, 9713GZ