Status:

UNKNOWN

Manipulation of Arterial Pressure in Acute Ischemic Stroke

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Stroke, Acute

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a controlled clinical trial among non thrombolysed acute ischemic stroke patients to determine the effects of three levels of arterial pressure on death and neurological disability. After the ...

Detailed Description

To maintain the tree levels of systolic arterial pressure during de first 24h we will use one of the two strategies:1) infusion of 500 to 1000ml of saline solution and/or norepinephrine solution to in...

Eligibility Criteria

Inclusion

  • Patients 18 years or older, with the first Acute Ischemic Stroke within the first 6 hours of the symptoms and not candidate to thrombolysis
  • We will also include patients with previous Ischemic Stroke with Ranking score 0 or 1

Exclusion

  • Improuvment of the symptoms rapidly (in the first 15 min after admission)
  • Seizures not related do the acute ischemic stroke
  • Previous ischemic stroke in the last 6 weeks and with Ranking score \> 1
  • Haemorrhagic stroke
  • Anticoagulation
  • Hypoglycemia
  • Shock
  • Acute heart failure

Key Trial Info

Start Date :

January 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2010

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT00848770

Start Date

January 1 2008

End Date

December 1 2010

Last Update

December 31 2009

Active Locations (1)

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Hospital de Clínicas de Porto Alegre/ UFRGS

Porto Alegre, Rio Grande do Sul, Brazil