Status:

WITHDRAWN

Mycophenolate Mofetil Maintenance Therapy for Liver Transplantation

Lead Sponsor:

University of Wisconsin, Madison

Conditions:

Primary Liver Transplant

Eligibility:

All Genders

45+ years

Phase:

NA

Brief Summary

The rationale for this study is to determine if Campath-1H can be used in liver transplant recipients to induce a state of immunological unresponsiveness that would not only eliminate the need for cal...

Eligibility Criteria

Inclusion

  • Male or female subjects;
  • Ages 45 years and older;
  • Are to receive a liver transplant.

Exclusion

  • Recipients of a multi-organ transplant;
  • known hypersensitivity to daclizumab, CellCept®, or prednisone;
  • therapy with an investigational medication within 4 weeks of study entry;
  • history of malignancies within the past 5 years and/or lymphoma, excluding adequately treated skin carcinoma (basal or squamous cell), or other than exclusion #9;
  • history of a psychological illness or condition such as to interfere with the patient's ability to understand the requirements of the study;
  • history of HIV infection;
  • females who are pregnant or nursing;
  • subject is receiving systemic corticosteroids for other medical conditions for which the physician feels that discontinuation of corticosteroids is contraindicated;
  • T2 or higher hepatocellular carcinoma

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00849238

Last Update

October 8 2015

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