Status:
COMPLETED
Comprehensive Treatment for Different Types of Tumor Thrombi in the Portal Vein for Hepatocellular Carcinoma Patients
Lead Sponsor:
Eastern Hepatobiliary Surgery Hospital
Conditions:
Hepatocellular Carcinoma
Portal Vein Tumor Thrombus
Eligibility:
All Genders
30-60 years
Phase:
PHASE2
Brief Summary
This study is working to evaluate the surgical comprehensive treatment for different types of tumor thrombi in the portal vein for hepatocellular carcinoma patients, to establish a standardized, unifi...
Detailed Description
Primary liver cancer (PLC) has a great tendency to invade portal vein intravascularly, results in the formation of portal vein tumor thrombus (PVTT), which is a crucial factor that can worsen the prog...
Eligibility Criteria
Inclusion
- Male or female patients \> 30 years and \<=60 years of age.
- with a clinical diagnosis of primary liver cancer with PVTT, without any adjuvant therapy.
- resectable tumors in the liver.
- PVTT type for II or III (based on the PVTT type system established by our groups), confirmed through pre-operative imaging and pathologic examination.
- liver function grade A or B of the Child-Pugh classification.
- No dysfunction in major organs; Blood routine, kidney function, cardiac function and lung function are basically normal. Hb ≥95g/L,WBC ≥3.000 cells/mm³,platelets ≥80.000 cells/mm³.
- Patients who can understand this trial and have signed information consent.
Exclusion
- have had an allergic reaction following iodine or chemotherapeutic drugs.
- with extrahepatic metastasis.
- Patients with apparent cardiac, pulmonary, cerebral and renal dysfunction,which may affect the treatment of liver cancer.
- liver function:Child C.
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00849264
Start Date
December 1 2008
End Date
December 1 2010
Last Update
April 1 2016
Active Locations (1)
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1
Eastern hepatobilliary surgery hospital
Shanghai, Shanghai Municipality, China, 200438