Status:
COMPLETED
Postoperative Cognitive Decline, Inflammation, and Plasma Levels of Beta-amyloids
Lead Sponsor:
NYU Langone Health
Conditions:
Postoperative Cognitive Dysfunction
Mild Cognitive Impairment
Eligibility:
All Genders
65+ years
Brief Summary
Postoperative cognitive dysfunction (POCD) can be a serious complication. The development of therapeutic strategies for the prevention and treatment of this condition requires the identification of su...
Detailed Description
We will recruit 50 patients 65 years and older scheduled for spine surgery. The design utilizes prospective serial assessments. The enrolled 50 surgical subjects will be evaluated preoperatively and p...
Eligibility Criteria
Inclusion
- Patients age 65 and older scheduled to undergo spine surgery.
- Subjects who are able to read and understand English
Exclusion
- Emergent nature of the procedure which might preclude the conduct of preoperative cognitive examination
- Participation in any other investigational intervention or clinical study
- History of psychiatric illnesses (except depression)
Key Trial Info
Start Date :
December 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2011
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT00850928
Start Date
December 1 2008
End Date
January 1 2011
Last Update
March 17 2016
Active Locations (1)
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1
NYU School of Medicine
New York, New York, United States, 10016