Status:
UNKNOWN
Pro-inflammatory Cytokines in Blood From Orthopedic Surgery Compared to Abdominal Aneurysm Repair
Lead Sponsor:
Sykehuset i Vestfold HF
Collaborating Sponsors:
Oslo University Hospital
Dentsply Sirona Implants and Consumables
Conditions:
Aortic Diseases
Osteoarthritis, Hip
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to investigate the contents in blood sampled from surgery site during hip replacement compared with blood sampled from abdominal aortic surgery. Is there any difference in...
Detailed Description
Patient (n= 10) scheduled for total hip replacement or hemiprosthesis and patient (n=10) scheduled for abdominal aortic surgery. Primary outcome: Pro-inflammatory cytokines (IL-6, IL-8 and TNF-α) an...
Eligibility Criteria
Inclusion
- ASA 1-4
Exclusion
- Patient using corticosteroids, NSAIDs or Cox-II inhibitors
- Patients under 18 years
- Patients who are included in pharmaceutical studies
- Opioids-, benzodiazepines-, antiepileptic drugs-, alcohol- and α2-agonists abuse
- Pregnant and breastfeeding women
- Patients with known hypersensitivity for opioids, propofol or volatile anesthetics
- Patients with serious arrhythmias (atrial fibrillation/flutter is acceptable)
- Uncontrolled hypertension, serious psychiatric disease
- Patients with unstable angina pectoris or myocardial infarction the last month before inclusion
- Acute abdominal aortic surgery (acute dissection or rupture)
- Planned laparoscopic abdominal aortic aneurysm surgery
- Transfusion of blood products last month before surgery
- Glucocorticoid users
Key Trial Info
Start Date :
November 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2010
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00851149
Start Date
November 1 2009
End Date
May 1 2010
Last Update
June 11 2010
Active Locations (1)
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1
Sykehuset i Vestfold HF
Tønsberg, Norway, 3103