Status:

COMPLETED

Non Invasive Pressure Support Ventilation (NIPPV) Versus Recruitment Maneuver (RM) and Preoxygenation

Lead Sponsor:

University Hospital, Clermont-Ferrand

Conditions:

Obesity

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare the effects of noninvasive pressure support ventilation and early alveolar recruitment maneuver during anesthesia induction of morbidly obese patients on both o...

Detailed Description

Atelectasis formation during general anesthesia, leading to reduced end-expiratory lung volume, is an important cause of intrapulmonary shunt leading to impaired gas-exchange and hypoxemia. During gen...

Eligibility Criteria

Inclusion

  • Body mass index (BMI \> 30 kg/m2)
  • Age \> 18 years
  • ASA I-III

Exclusion

  • Age \< 18 years
  • Patient refusal
  • Pregnancy
  • Emergency surgery
  • COPD with FEV1 \< 50%
  • History of pneumothorax
  • Severe asthma
  • Cardiac failure (NYHA \> 2)
  • Ischemic heart disease

Key Trial Info

Start Date :

February 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2009

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00852384

Start Date

February 1 2009

End Date

August 1 2009

Last Update

August 28 2009

Active Locations (1)

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1

University Hospital Hôtel-Dieu

Clermont-Ferrand, France, 63058