Status:

COMPLETED

Cardiorespiratory Changes in Patients Being Weaned Off Mechanical Ventilation

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Critical Care

Weaning

Eligibility:

All Genders

18+ years

Brief Summary

The objective of this study was to analyze changes in cardiac function using Doppler echocardiogram in critical patients during weaning from mechanical ventilation using two different weaning methods ...

Detailed Description

Weaning from mechanical ventilation (MV) involves physiological changes that can overload the cardiorespiratory system due to changes in the interaction between patient and ventilator. This was a ran...

Eligibility Criteria

Inclusion

  • patients hemodynamically stable
  • conscious (Glasgow scale ≥ 13)
  • with adequate gaseous exchange (O2 saturation ≥ 95%, fraction of inspired oxygen (FiO2) ≤ 40% and positive end-expiratory pressure (PEEP) = 5
  • with no acidosis or alkalosis)
  • normal electrolyte levels
  • presence of respiratory drive
  • informed consent was signed by the patients and/or family members

Exclusion

  • hemodynamic instability
  • severe intracranial disease
  • barotrauma

Key Trial Info

Start Date :

December 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2007

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00852891

Start Date

December 1 2005

End Date

August 1 2007

Last Update

February 27 2009

Active Locations (1)

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1

Federal University of Rio Grande do Sul

Porto Alegre, Rio Grande do Sul, Brazil