Status:

COMPLETED

The Standard Concentration of Morphine as a Positive Control for Intradermal Skin Test

Lead Sponsor:

Chulalongkorn University

Conditions:

Intradermal Test

Eligibility:

All Genders

18-60 years

Brief Summary

This study aims to compare skin reactivity results between morphine and histamine as a positive control agents in intradermal skin test.

Detailed Description

Histamine hydrochloride and different concentrations of morphine sulfate will be intradermally injected and wheal diameter size will be comparatively measured between 15-30 minutes' time points after ...

Eligibility Criteria

Inclusion

  • age 18-60 years old

Exclusion

  • immunodeficiency state
  • cancer
  • severe skin diseases
  • severe medical illnesses
  • malnutrition
  • uncontrolled asthma
  • pregnancy
  • received oral or systemic corticosteroid within 1 month before this study
  • receiving immunosuppressive agents
  • taken antihistamine within 3 days before this study
  • taking beta-blocker
  • previous history of immunotherapy
  • have hypersensitivity reaction to morphine/opiates

Key Trial Info

Start Date :

March 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2009

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT00853476

Start Date

March 1 2009

End Date

October 1 2009

Last Update

February 18 2011

Active Locations (1)

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Faculty of Medicine, Chulalongkorn University

Bangkok, Thailand, 10330