Status:

COMPLETED

Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Mycophenolate Mofetil

Lead Sponsor:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborating Sponsors:

Dartmouth-Hitchcock Medical Center

Conditions:

Systemic Sclerosis

Eligibility:

All Genders

19-90 years

Brief Summary

The purpose of this study is to assess whether skin biopsy specimens from patients with diffuse cutaneous systemic sclerosis (dcSSc) can be used as biomarkers (measures of activity and type) of diseas...

Detailed Description

Systemic sclerosis (SSc) is an autoimmune connective tissue disease primarily affecting young to middle-aged women. The pathogenesis of SSc is complex involving interplay of three seemingly diverse pr...

Eligibility Criteria

Inclusion

  • 18 years of age
  • systemic sclerosis

Exclusion

  • pregnant
  • bleeding disorder
  • history of delayed wound healing

Key Trial Info

Start Date :

November 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00853788

Start Date

November 1 2008

End Date

June 1 2011

Last Update

February 17 2012

Active Locations (1)

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1

Northwestern Memorial Faculty Foundation

Chicago, Illinois, United States, 60611