Status:

COMPLETED

Enhance of Language Learning with Neurostimulation

Lead Sponsor:

Universitätsklinikum Hamburg-Eppendorf

Collaborating Sponsors:

German Research Foundation

Conditions:

Stroke

Aphasia

Eligibility:

All Genders

18-86 years

Phase:

NA

Brief Summary

The purpose of this study is to test the effect of transcranial direct current stimulation over the motor cortex of the language dominant hemisphere on language learning in healthy subjects and stroke...

Detailed Description

The motor cortex is involved at different levels of language processing. It has been demonstrated that the perception of action words activates motor representations in the language-dominant hemispher...

Eligibility Criteria

Inclusion

  • age \>18 and \< 86 years
  • contractual capability
  • ischemic stroke excluding motor cortex (stroke patients)
  • minimum time since stroke 9 months
  • aphasia (stroke patients)
  • severe aphasia that impedes understanding of instructions (stroke patients)

Exclusion

  • sever head trauma in the past
  • seizures
  • pace maker
  • metal implants in the head/neck region
  • severe comorbidity, especially neurologic and psychiatric diseases
  • intake of illegal drugs
  • Mini Mental State examination score \< 27
  • neuroactive substances, e.g. antidepressants
  • pregnancy

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00854893

Start Date

October 1 2009

End Date

July 1 2010

Last Update

December 11 2024

Active Locations (1)

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1

University Hospital Hamburg-Eppendorf, Department of Neurology

Hamburg, Hamburg, Germany, 20246