Status:
TERMINATED
Metabolic Syndrome in Bone Marrow Transplant Survivors
Lead Sponsor:
Nationwide Children's Hospital
Conditions:
Metabolic Syndrome
Eligibility:
All Genders
9-23 years
Phase:
NA
Brief Summary
Life for long-term bone marrow transplant patients is complicated by endocrine late effects including growth hormone (GH) deficiency, thyroid hormone deficiency and sex steroid deficiency. Recently, s...
Detailed Description
Specific aim 1: Surveillance for endocrinopathy * We will test for defects in the growth hormone (GH) axis utilizing GH stimulation testing. Briefly the patient (subject) will have studies conducted ...
Eligibility Criteria
Inclusion
- One year post BMT in autogenic transplanted patients and two years from BMT in allogenic transplanted patients
- The participants may be from any ethnic group and of either gender
- Free of the following chronic medical illness (diseases possibly associated with glucose intolerance or altered insulin sensitivity): type 1 DM, HIV, chronic liver disease, cystic fibrosis, chronic renal failure, known genetic syndrome.
Exclusion
- On-going graft vs. host disease
- Use of Megace® or another progestational agent
- Use of anabolic steroids
- Diagnosis of one of the chronic diseases listed above
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT00855244
Start Date
March 1 2009
End Date
May 1 2010
Last Update
May 18 2015
Active Locations (1)
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1
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205