Status:
COMPLETED
The Effect of Amiloride and Spironolactone in Healthy Persons
Lead Sponsor:
Regional Hospital Holstebro
Conditions:
High Blood Pressure
Eligibility:
All Genders
18-40 years
Phase:
PHASE1
Brief Summary
This study will investigate whether retaining potassium in the body will lead to changes in blood pressure and changes in blood and urine samples.
Detailed Description
The purpose is to measure the effect of amiloride and spironolactone on: 1. Renal function (GFR, u-AQP2, u-ENaCβ, u-cAMP, u-PGE2, CH20, FENa, FEK), 2. Pulsbewave velocity, augmentation index and cent...
Eligibility Criteria
Inclusion
- Healthy
- Non-smokers
Exclusion
- Smoking
- Under medical treatment
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00857909
Start Date
January 1 2009
End Date
July 1 2010
Last Update
July 8 2011
Active Locations (1)
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1
Medical Research
Holstebro, Denmark, 7500