Status:
COMPLETED
Association of Genes to Resistance to Weight Loss in Obese Patients
Lead Sponsor:
Interleukin Genetics, Inc.
Conditions:
Obesity
Metabolic Syndrome
Eligibility:
All Genders
21-70 years
Brief Summary
The overall goal of this study is to determine whether variations in the perilipin, and several other, genes would be a useful tool for physicians who are caring for morbidly obese patients to guide t...
Detailed Description
The PRIMARY goal of this study is to investigate the association of perilipin gene polymorphisms, with obese subjects who are "resistant" to weight loss in a defined program. The SECONDARY goal of th...
Eligibility Criteria
Inclusion
- Caucasian
- competent patients interested in Gastric Bypass Surgery
- patients who are eligible for Gastric Bypass Surgery based on NIH criteria:
- Male or Female
- 21 - 70 years old, inclusive
- Body Mass Index (BMI) \> 40 with 2 co-morbid conditions such as Sleep Apnea, Hypertension, or Type 2 Diabetes
- BMI \> 45 with no co-morbid conditions
Exclusion
- Patients not interested in Gastric Bypass Surgery
- Patients who do not qualify for surgery based on medical contraindications
- Patients with severe psychological contraindications
- Patients not willing to be compliant with pre-post surgical recommendations
- Patients younger than 21 years of age
- Patients older than 70 years of age
- Patients who do not qualify for surgery based on insurance constraints i.e., insurance guidelines for bypass surgery
- Patients who are pregnant
- Hispanic, Black, Asian Races
- Abnormal thyroid function
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
824 Patients enrolled
Trial Details
Trial ID
NCT00858221
Start Date
August 1 2008
End Date
July 1 2009
Last Update
October 20 2009
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Geisinger Health System
Danville, Pennsylvania, United States, 17822