Status:
UNKNOWN
International PFO Consortium
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Collaborating Sponsors:
University Hospital, Basel, Switzerland
University of Lausanne Hospitals
Conditions:
Stroke
Transient Ischemic Attack
Eligibility:
All Genders
18+ years
Brief Summary
The prevalence of patent foramen ovale (PFO) is about 25% in the general population and approximately 40% in patients who have ischemic stroke of unknown cause (cryptogenic stroke). Given the large nu...
Detailed Description
Background The prevalence of patent foramen ovale (PFO) is about 25% in the general population and approximately 40% in patients who have ischemic stroke of unknown cause (cryptogenic stroke). Given ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Age \> 18 years
- Diagnosis of PFO established by transesophageal echocardiography (TEE)
- Ischemic stroke or transient ischemic attack within the previous 6 months
- Exclusion Criteria
- Non-vascular origin of the neurological symptoms after brain imaging (CT scan or MRI)
- Comorbid condition that would interfere with the study
- Pregnancy
- History of intracranial bleeding, confirmed arterio-venous malformation, aneurysm or uncontrolled coagulopathy
- Contraindications for TEE, echocardiographic or iodine contrast media
Exclusion
Key Trial Info
Start Date :
September 8 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2021
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT00859885
Start Date
September 8 2008
End Date
December 1 2021
Last Update
December 12 2017
Active Locations (18)
Enter a location and click search to find clinical trials sorted by distance.
1
Tufts Medical Center
Boston, Massachusetts, United States, 02111
2
Baystate Medical Center
Springfield, Massachusetts, United States, 01199
3
East Medical Center
Tyler, Texas, United States, 75710
4
University Hospital Gent
Ghent, Belgium, 9000