Status:
COMPLETED
Advance Targeted Transfusion in Anemic Cardiac Surgical Patients for Kidney Protection: A Proof of Concept Pilot Study
Lead Sponsor:
University Health Network, Toronto
Conditions:
Kidney Injury
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
One of the major complications of heart surgery is kidney injury, which occurs in up to 30% of patients and is associated with poor outcomes including death. We have found that patients whose hemoglob...
Eligibility Criteria
Inclusion
- Patients undergoing non-emergent aortocoronary bypass (ACB) surgery, or valve surgery, combined ACB and valve, or aortic root repair requiring CPB with a preoperative Hb concentration between 100 and 120 g/L.
Exclusion
- Any conditions that may limit the ability of patients to tolerate the intervention:
- Severe aortic or mitral valve stenosis
- History of congestive heart failure within 30 days of surgery or severe ventricular dysfunction (ejection fraction \< 30%)
- Severe (\> 60%) left main coronary artery stenosis or unstable angina within 30 days of surgery
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2011
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00861822
Start Date
July 1 2009
End Date
July 1 2011
Last Update
February 25 2013
Active Locations (1)
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1
Toronto General Hospital, University Health Network
Toronto, Ontario, Canada, M5G 2C4